A treatment for severe nodular acne: a randomized investigator-blinded, controlled, noninferiority trial comparing fixed-dose adapalene/benzoyl peroxide plus doxycycline vs. oral isotretinoin

201450 citationsJournal Article

Authors

Jerry Tan · Western University

Shannon Humphrey · University of British Columbia

Ronald Vender · Dermatrials Research

Benjamin Barankin · Occupational Cancer Research Centre

Melinda Gooderham · SKiN Health

Nabil Kerrouche · Galderma (France)

F. Audibert ·

Abstract

D+A/BPO showed a favourable composite efficacy/safety profile compared with ISO. This combination is an alternative to ISO in patients intolerant to, or unable or unwilling to take, oral ISO, and is an option for treatment of severe nodular acne.

Topics & Keywords

Acne and Rosacea Treatments and Effects Nonmelanoma Skin Cancer Studies Dermatologic Treatments and Research

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: British Journal of Dermatology

Volume 171, Issue 6, pp. 1508-1516

DOI: 10.1111/bjd.13191

Field-Weighted Citation Impact: 6.81