Angiotensin II Induces LOX-1, the Human Endothelial Receptor for Oxidized Low-Density Lipoprotein

1999255 citationsJournal Article

Authors

Henning Morawietz · Social Neuroscience Lab

Uwe Rueckschloss · Social Neuroscience Lab

Bernd Niemann · Social Neuroscience Lab

Nicole Duerrschmidt · Social Neuroscience Lab

Jan Galle · Social Neuroscience Lab

K. Hakim · Social Neuroscience Lab

Hans‐Reinhard Zerkowski ·

Abstract

We conclude that LOX-1 is regulated by Ang II in vitro and in vivo, that induction of LOX-1 is mediated by the AT(1) receptor, and that repression of LOX-1 by long-term ACE inhibitor treatment may contribute to the antiatherosclerotic potential of this therapy.

Topics & Keywords

Atherosclerosis and Cardiovascular Diseases Inflammatory mediators and NSAID effects

Publication Details

Published in: Circulation

Volume 100, Issue 9, pp. 899-902

DOI: 10.1161/01.cir.100.9.899

Field-Weighted Citation Impact: 6.10

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Angiotensin II Induces LOX-1, the Human Endothelial Receptor for Oxidized Low-Density Lipoprotein

Authors

Abstract

Topics & Keywords

Publication Details