Inhibiting Mitochondrial Fission Protects the Heart Against Ischemia/Reperfusion Injury

2010953 citationsJournal Article

Authors

Sang‐Bing Ong · University College Hospital

Sapna Subrayan · University College Hospital

Shiang Y. Lim · University College Hospital

Derek M. Yellon · University College Hospital

Sean M. Davidson · University College Hospital

Derek J. Hausenloy · University College Hospital

Abstract

Inhibiting mitochondrial fission protects the heart against ischemia/reperfusion injury, suggesting a novel pharmacological strategy for cardioprotection.

Topics & Keywords

Mitochondrial Function and Pathology ATP Synthase and ATPases Research Cardiac Ischemia and Reperfusion

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Circulation

Volume 121, Issue 18, pp. 2012-2022

DOI: 10.1161/circulationaha.109.906610

Field-Weighted Citation Impact: 23.59