Systemic inflammation and disease progression in Alzheimer disease

20091,117 citationslettergreen Open Access

Authors

Clive Holmes · Moorgreen Hospital

Colm Cunningham · Moorgreen Hospital

E. Zotova · Moorgreen Hospital

Janet Woolford · Moorgreen Hospital

C. Dean · Moorgreen Hospital

Steven Kerr · Moorgreen Hospital

David Culliford · Moorgreen Hospital

Abstract

Both acute and chronic systemic inflammation, associated with increases in serum tumor necrosis factor alpha, is associated with an increase in cognitive decline in Alzheimer disease.

Topics & Keywords

Alzheimer's disease research and treatments Tryptophan and brain disorders Neuroinflammation and Neurodegeneration Mechanisms

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Neurology

Volume 73, Issue 10, pp. 768-774

DOI: 10.1212/wnl.0b013e3181b6bb95

Field-Weighted Citation Impact: 24.13