A High-Speed Congenic Strategy Using First-Wave Male Germ Cells

200950 citationsJournal Articlegold Open Access

Authors

Narumi Ogonuki · RIKEN BioResource Research Center

Kimiko Inoue · RIKEN BioResource Research Center

Michiko Hirose · RIKEN BioResource Research Center

Ikuo Miura · RIKEN BioResource Research Center

Keiji Mochida · RIKEN BioResource Research Center

Takahiro Sato · The University of Tokyo

Nathan Mise

Abstract

This new high-speed breeding strategy enables us to produce congenic strains within about half a year. It should provide the fastest protocol for precise definition of the phenotypic effects of genes of interest on desired genetic backgrounds.

Topics & Keywords

Animal Genetics and Reproduction Reproductive Biology and Fertility Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities

Publication Details

Published in: PLoS ONE

Volume 4, Issue 3, pp. e4943-e4943

DOI: 10.1371/journal.pone.0004943

Field-Weighted Citation Impact: 2.30

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A High-Speed Congenic Strategy Using First-Wave Male Germ Cells

Authors

Abstract

Topics & Keywords

Publication Details