Serum MicroRNA-155 as a Potential Biomarker to Track Disease in Breast Cancer

2012238 citationsJournal Articlegold Open Access

Authors

Yu Sun · National Center for Clinical Laboratories

Minjie Wang · Chinese Academy of Medical Sciences & Peking Union Medical College

Guigao Lin · Chinese Academy of Medical Sciences & Peking Union Medical College

Shipeng Sun · Guang’anmen Hospital

Xuexiang Li · Chinese Academy of Medical Sciences & Peking Union Medical College

Jun Qi · Chinese Academy of Medical Sciences & Peking Union Medical College

Abstract

Our results suggest that serum miR-155 is a potential biomarker to discriminate breast cancer patients from healthy subjects. For the first time, we demonstrated a declined trend of miR-155 after surgery and chemotherapy, which raises the possibility to use it as an indicator for treatment response.

Topics & Keywords

MicroRNA in disease regulation Cancer-related molecular mechanisms research Circular RNAs in diseases

UN Sustainable Development Goals

Reduced inequalities

Publication Details

Published in: PLoS ONE

Volume 7, Issue 10, pp. e47003-e47003

DOI: 10.1371/journal.pone.0047003

Field-Weighted Citation Impact: 8.97