Peripheral Inflammatory Cytokines as Biomarkers in Alzheimer’s Disease and Mild Cognitive Impairment

2007149 citationsJournal Article

Authors

Rita Guerreiro · University of Coimbra

Isabel Santana · University of Coimbra

José Brás · Centro de Neurociências e Biologia Celular

Beatriz Santiago · University of Coimbra

Artur Paiva · Instituto Português de Oncologia de Coimbra Francisco Gentil

Catarina R. Oliveira · Centro de Neurociências e Biologia Celular

Abstract

These results agree with a persistent inflammatory status in AD, reinforcing the hypothesis of a progressive impairment of the immune response in this disorder and suggesting that monocytes may be good targets to study the progression from MCI to AD.

Topics & Keywords

Alzheimer's disease research and treatments Neuroinflammation and Neurodegeneration Mechanisms Tryptophan and brain disorders

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Neurodegenerative Diseases

Volume 4, Issue 6, pp. 406-412

DOI: 10.1159/000107700

Field-Weighted Citation Impact: 5.16