Dispersion of refractoriness in normal and ischaemic canine ventricle: effects of sympathetic stimulation

199392 citationsJournal Article

Authors

Tobias Opthof · University of Amsterdam

Ruben Coronel

Jessica Vermeulen

Hein J. Verberne

Frans J.L. van Capelle

Michiel J. Janse

Abstract

Due to opposite effects on normal and ischaemic myocardium, sympathetic stimulation increases the difference in refractoriness over the ischaemic border. This may enhance the chance for regional conduction block and the propensity to re-entrant arrhythmias.

Topics & Keywords

Cardiac electrophysiology and arrhythmias Cardiac Arrhythmias and Treatments ECG Monitoring and Analysis

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Cardiovascular Research

Volume 27, Issue 11, pp. 1954-1960

DOI: 10.1093/cvr/27.11.1954

Field-Weighted Citation Impact: 1.38