Periaqueductal Gray Matter Dysfunction in Migraine: Cause or the Burden of Illness?

2001619 citationsJournal Article

Authors

K.M.A. Welch · University of Kansas Medical Center

Sheena K. Aurora · Neurosciences Institute

Abstract

Iron homeostasis in the PAG was selectively, persistently, and progressively impaired in the EM and CDH groups, possibly caused by repeated migraine attacks. These results support and emphasize the role of the PAG as a possible "generator" of migraine attacks, potentially by dysfunctional control of the trigeminovascular nociceptive system.

Topics & Keywords

Migraine and Headache Studies Trigeminal Neuralgia and Treatments Ophthalmology and Eye Disorders

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Headache The Journal of Head and Face Pain

Volume 41, Issue 7, pp. 629-637

DOI: 10.1046/j.1526-4610.2001.041007629.x

Field-Weighted Citation Impact: 14.45