Randomized trial of carboplatin plus amifostine versus carboplatin alone in patients with advanced solid tumors

199750 citationsJournal Article

Authors

G. Thomas Budd · Cleveland Clinic

Ram Ganapathi · Cleveland Clinic

David J. Adelstein · Cleveland Clinic

Robert Pelley · Cleveland Clinic

Thomas Olencki · Cleveland Clinic

John Petrus · Akron General Medical Center

Denise McLain ·

Abstract

These data support the hypothesis that amifostine attenuates the myelosuppression of carboplatin. Additional studies of amifostine in combination with carboplatin-containing chemotherapy regimens are warranted.

Topics & Keywords

Neutropenia and Cancer Infections Lung Cancer Research Studies Cancer Treatment and Pharmacology

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Cancer

Volume 80, Issue 6, pp. 1134-1140

DOI: 10.1002/(sici)1097-0142(19970915)80:6<1134::aid-cncr17>3.0.co;2-9

Field-Weighted Citation Impact: 1.47