The Chemistry of α-Haloketones and Their Utility in Heterocyclic Synthesis

2003218 citationsJournal Articlegold Open Access

Authors

Hatem M. Gaber · National Organization for Drug Control and Research

Abstract

The molecular structures and spectral properties of α-haloketones as well as their syntheses are analyzed and reviewed. Their reactivity towards oxygen, nitrogen, and sulfur nucleophiles, carboxylic acids, carbon nucleophiles, alkenes, and alkynes are discussed.

Topics & Keywords

Organic Chemistry Cycloaddition Reactions Chemical Synthesis and Reactions Chemical Reaction Mechanisms

UN Sustainable Development Goals

Clean water and sanitation

Publication Details

Published in: Molecules

Volume 8, Issue 11, pp. 793-865

DOI: 10.3390/81100793

Field-Weighted Citation Impact: 1.93