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Apoptosis in Myocytes in End-Stage Heart Failure

19961,443 citationsJournal Articlebronze Open Access

Authors

Jagat Narula · Harvard University

Nezam Haider · Northeastern University

Renu Virmani · Armed Forces Institute of Pathology

Thomas G. DiSalvo · Massachusetts General Hospital

Frank D. Kolodgie · Armed Forces Institute of Pathology

Roger J. Hajjar · Harvard University

Abstract

Loss of myocytes due to apoptosis occurs in patients with end-stage cardiomyopathy and may contribute to progressive myocardial dysfunction.

Topics & Keywords

Cell death mechanisms and regulation Viral Infections and Immunology Research CRISPR and Genetic Engineering

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 335, Issue 16, pp. 1182-1189

DOI: 10.1056/nejm199610173351603

Field-Weighted Citation Impact: 29.72

Apoptosis in Myocytes in End-Stage Heart Failure | Researchclopedia

· Harvard University

Marc J. Semigran · Massachusetts General Hospital

G. William Dec · Harvard University

Ban-An Khaw · Massachusetts General Hospital