Vitamin D Conversion by Sarcoid Lymph Node Homogenate

1984267 citationsJournal Article

Authors

Rebecca S. Mason · St. Leonards Hospital

YUK-LUEN CHAN · Australian Veterinary Association

DIANNE LISSNER · Australian Veterinary Association

SOLOMON POSEN · Australian Veterinary Association

Abstract

Recent studies suggest that hypercalcemia of sarcoidosis is due to high blood concentrations of calcitriol and that this compound may be synthesized at an extra-renal site. We report that sarcoid lymph node homogenate metabolized calcifediol to a substance indistinguishable from calcitriol, whereas six nonsarcoid lymph nodes failed to produce this compound.

Topics & Keywords

Sarcoidosis and Beryllium Toxicity Research Drug-Induced Adverse Reactions Bone health and treatments

Publication Details

Published in: Annals of Internal Medicine

Volume 100, Issue 1, pp. 59-61

DOI: 10.7326/0003-4819-100-1-59

Field-Weighted Citation Impact: 23.77

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Vitamin D Conversion by Sarcoid Lymph Node Homogenate

Authors

Abstract

Topics & Keywords

Publication Details