Use of plasma DNA in detection of loss of heterozygosity in patients with multiple myeloma

200315 citationsJournal Article

Authors

Maha Ahmed · The University of Texas MD Anderson Cancer Center

Francis J. Giles · The University of Texas MD Anderson Cancer Center

Youngson Joe · The University of Texas MD Anderson Cancer Center

Donna M. Weber · Myeloma UK

Iman Jilani · The University of Texas MD Anderson Cancer Center

Taghi Manshouri · The University of Texas MD Anderson Cancer Center

Sergio Giralt

Abstract

PB plasma appears to be enriched by tumor-specific DNA and can be used to detect chromosomal abnormalities in patients with MM. Further studies are needed to establish the clinical relevance of this approach in comparison with other techniques.

Topics & Keywords

Multiple Myeloma Research and Treatments Chromosomal and Genetic Variations Cancer Genomics and Diagnostics

UN Sustainable Development Goals

No poverty

Publication Details

Published in: European Journal Of Haematology

Volume 71, Issue 3, pp. 174-178

DOI: 10.1034/j.1600-0609.2003.00125.x

Field-Weighted Citation Impact: 0.51