Influence of Genes and Environment on Brain Volumes in Twin Pairs Concordant and Discordant for Bipolar Disorder

2009114 citationsJournal Articlebronze Open Access

Authors

Astrid C. van der Schot · University Medical Center Utrecht

Ronald Vonk · University of Groningen

Rachel G.H. Brans · University Medical Center Utrecht

Neeltje E.M. van Haren · University Medical Center Utrecht

P. Cédric M. P. Koolschijn · University Medical Center Utrecht

Valerie Nuboer · University Medical Center Utrecht

Hugo G. Schnack

Abstract

Focusing on genes controlling white matter integrity may be a fruitful strategy in the quest to discover genes implicated in bipolar disorder. Elucidating the mechanism by which lithium attenuates brain matter loss may lead to the development of neuroprotective drugs.

Topics & Keywords

Bipolar Disorder and Treatment Genetics and Neurodevelopmental Disorders Genetic Syndromes and Imprinting

UN Sustainable Development Goals

Life in Land

Publication Details

Published in: Archives of General Psychiatry

Volume 66, Issue 2, pp. 142-142

DOI: 10.1001/archgenpsychiatry.2008.541

Field-Weighted Citation Impact: 8.23