Effects of obstructive sleep apnea on endothelin-1 and blood pressure

1999456 citationsJournal Article

Authors

Bradley G. Phillips · University of Iowa

Krzysztof Narkiewicz · University of Iowa

Catherine A. Pesek · University of Iowa

William G. Haynes · University of Iowa

Mark Eric Dyken

Virend K. Somers · University of Iowa

Abstract

Sleep apnea elicits increases in blood pressure and endothelin-1, with reductions in both after treatment. Vasoconstrictor and mitogenic effects of endothelin-1 may be implicated in increased cardiovascular risk in patients with obstructive sleep apnea.

Topics & Keywords

Obstructive Sleep Apnea Research Neuroscience of respiration and sleep Nitric Oxide and Endothelin Effects

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of Hypertension

Volume 17, Issue 1, pp. 61-66

DOI: 10.1097/00004872-199917010-00010

Field-Weighted Citation Impact: 4.16