Pre-Analytical Conditions in Non-Invasive Prenatal Testing of Cell-Free Fetal RHD

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Authors

Frederik Banch Clausen · Copenhagen University Hospital

Tanja Roien Jakobsen · Rigshospitalet

Klaus Rieneck · Copenhagen University Hospital

Grethe Risum Krog · Copenhagen University Hospital

Leif Kofoed Nielsen · Copenhagen University Hospital

Ann Tabor · Copenhagen University Hospital

Morten Hanefeld Dziegiel

Abstract

The setup for real-time PCR-based, non-invasive prenatal testing of cffDNA in the Capital Region of Denmark is very robust. Our findings regarding the transportation of blood samples demonstrate the high stability of cffDNA. The applicability of a universal standard curve facilitates easy cffDNA quantification.

Topics & Keywords

Prenatal Screening and Diagnostics Parvovirus B19 Infection Studies Fetal and Pediatric Neurological Disorders

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: PLoS ONE

Volume 8, Issue 10, pp. e76990-e76990

DOI: 10.1371/journal.pone.0076990

Field-Weighted Citation Impact: 6.83