Identification of Osteopontin as a Novel Marker for Early Hepatocellular Carcinoma

2011321 citationsJournal Articlebronze Open Access

Authors

Sufen Shang · Fred Hutch Cancer Center

Amelie Plymoth · Fred Hutch Cancer Center

Shaokui Ge · Fred Hutch Cancer Center

Ziding Feng · Fred Hutch Cancer Center

Hugo R. Rosen · University of Colorado Denver

Suleeporn Sangrajrang · National Cancer Institute of Thailand

Pierre Hainaut

Abstract

OPN was more sensitive than AFP for the diagnosis of HCC in all studied HCC groups. In addition, OPN performance remained intact in samples collected 1 year before diagnosis.

Topics & Keywords

Bone and Dental Protein Studies Liver Disease Diagnosis and Treatment Cancer, Hypoxia, and Metabolism

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Hepatology

Volume 55, Issue 2, pp. 483-490

DOI: 10.1002/hep.24703

Field-Weighted Citation Impact: 14.21