TDP‐43 immunoreactivity in hippocampal sclerosis and Alzheimer's disease

2007902 citationsJournal Articlegreen Open Access

Authors

Catalina Amador · Jacksonville College

Wen‐Lang Lin · Mayo Clinic in Florida

Zeshan Ahmed · Jacksonville College

David Personett · Jacksonville College

Peter Davies · Albert Einstein College of Medicine

Ranjan Duara · Mount Sinai Medical Center

Neill R. Graff‐Radford ·

Abstract

These results suggest that as many as 20% of AD cases and more than 70% of HpScl cases have pathology similar to that found in FTLD-U. Whether this represents concomitant FTLD-U or is analogous to colocalization of alpha-synuclein and tau in AD, reflecting a propensity for codeposition of abnormal protein conformers, remains to be determined.

Topics & Keywords

Alzheimer's disease research and treatments Parkinson's Disease Mechanisms and Treatments Amyotrophic Lateral Sclerosis Research

Publication Details

Published in: Annals of Neurology

Volume 61, Issue 5, pp. 435-445

DOI: 10.1002/ana.21154

Field-Weighted Citation Impact: 30.80

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TDP‐43 immunoreactivity in hippocampal sclerosis and Alzheimer's disease

Authors

Abstract

Topics & Keywords

Publication Details