Sequence diversity and haplotype structure in the human ABCB1 (MDR1, multidrug resistance transporter) gene

2003431 citationsJournal Article

Authors

Deanna L. Kroetz · GTx (United States)

Christiane Pauli‐Magnus

Joseph DeYoung · Institut thématique Génétique, génomique et bioinformatique

Travis R. Taylor · Institut thématique Génétique, génomique et bioinformatique

Abstract

This study represents a comprehensive analysis of ABCB1 nucleotide diversity and haplotype structure in different populations and illustrates the importance of haplotype considerations in characterizing the functional consequences of ABCB1 polymorphisms.

Topics & Keywords

Drug Transport and Resistance Mechanisms Trace Elements in Health Pharmacological Effects and Toxicity Studies

UN Sustainable Development Goals

Life in Land

Publication Details

Published in: Pharmacogenetics

Volume 13, Issue 8, pp. 481-494

DOI: 10.1097/00008571-200308000-00006

Field-Weighted Citation Impact: 11.44