Complement activating antibodies to myelin oligodendrocyte glycoprotein in neuromyelitis optica and related disorders

2011441 citationsJournal Articlegold Open Access

Authors

Simone Mader · Innsbruck Medical University

Viktoria Gredler · Innsbruck Medical University

Kathrin Schanda · Innsbruck Medical University

Kevin Rostásy · Innsbruck Medical University

Irena Dujmović · Centar za Promociju Nauke

Kristian Pfaller · Innsbruck Medical University

Andreas Lutterotti

Abstract

We could show for the first time that a subset of AQP4-IgG seronegative patients with NMO and HR-NMO exhibit a MOG-IgG mediated immune response, whereas MOG is not a target antigen in cases with an AQP4-directed humoral immune response.

Topics & Keywords

Multiple Sclerosis Research Studies Peripheral Neuropathies and Disorders Systemic Lupus Erythematosus Research

UN Sustainable Development Goals

Clean water and sanitation

Publication Details

Published in: Journal of Neuroinflammation

Volume 8, Issue 1, pp. 184-184

DOI: 10.1186/1742-2094-8-184

Field-Weighted Citation Impact: 14.05

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