Seroconversion to Multiple Islet Autoantibodies and Risk of Progression to Diabetes in Children

20131,231 citationsJournal Articlegreen Open Access

Authors

Anette G. Ziegler · Helmholtz Zentrum München

Marian Rewers · University of Colorado Denver

Olli Simell · University of Turku

Tuula Simell · University of Turku

Johanna Lempainen · University of Turku

Andrea K. Steck · University of Colorado Denver

Christiane Winkler ·

Abstract

The majority of children at risk of type 1 diabetes who had multiple islet autoantibody seroconversion progressed to diabetes over the next 15 years. Future prevention studies should focus on this high-risk population.

Topics & Keywords

Diabetes and associated disorders Pancreatic function and diabetes Diabetes Management and Research

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: JAMA

Volume 309, Issue 23, pp. 2473-2473

DOI: 10.1001/jama.2013.6285

Field-Weighted Citation Impact: 56.66