The Predictive Value of Stable Precursor Fragments of Vasoactive Peptides in Patients with Chronic Heart Failure: Data from the GISSI-Heart Failure (GISSI-HF) Trial

In patients with chronic and stable HF enrolled in a multicentre, randomized, clinical trial, measurement of stable precursor fragments of vasoactive peptides provided prognostic information independent of natriuretic peptides which are currently the best biomarkers for risk stratification.