Statistical and Biological Gene-Lifestyle Interactions of MC4R and FTO with Diet and Physical Activity on Obesity: New Effects on Alcohol Consumption

201280 citationsJournal Articlegold Open Access

Authors

Dolores Corella · Universitat de València

Carolina Ortega‐Azorín · Universitat de València

José V. Sorlí · Universitat de València

María‐Isabel Covas · Instituto de Salud Carlos III

Paula Carrasco · Instituto de Salud Carlos III

Jordi Salas‐Salvadó · Universidad Rovira i Virgili

Miguel Ángel Martínez‐González

Abstract

Statistical and biological interactions with PA and diet modulate the effects of FTO and MC4R polymorphisms on obesity. The novel association with alcohol consumption seems independent of their effects on BMI.

Topics & Keywords

Biochemical Analysis and Sensing Techniques Regulation of Appetite and Obesity Genetic Associations and Epidemiology

Publication Details

Published in: PLoS ONE

Volume 7, Issue 12, pp. e52344-e52344

DOI: 10.1371/journal.pone.0052344

Field-Weighted Citation Impact: 5.01

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Statistical and Biological Gene-Lifestyle Interactions of MC4R and FTO with Diet and Physical Activity on Obesity: New Effects on Alcohol Consumption

Authors

Abstract

Topics & Keywords

Publication Details