AceView: a comprehensive cDNA-supported gene and transcripts annotation

2006643 citationsJournal Articlegold Open Access

Authors

Danielle Thierry‐Mieg · National Institutes of Health

Jean Thierry‐Mieg · National Institutes of Health

Abstract

Relative to a consensus mRNA catalog constructed from all evidence-based annotations, Gencode and AceView have 81% and 84% sensitivity, and 74% and 73% specificity, respectively. This close agreement validates a richer view of the human transcriptome, with three to five times more transcripts than in UCSC Known Genes (sensitivity 28%), RefSeq (sensitivity 21%) or Ensembl (sensitivity 19%).

Topics & Keywords

Genomics and Phylogenetic Studies RNA and protein synthesis mechanisms Machine Learning in Bioinformatics

UN Sustainable Development Goals

Partnerships for the goals

Publication Details

Published in: Genome biology

Volume 7, Issue S1, pp. S12.1-14

DOI: 10.1186/gb-2006-7-s1-s12

Field-Weighted Citation Impact: 12.34