Comparison of Dopamine and Norepinephrine in the Treatment of Shock

20101,879 citationsJournal Articlebronze Open Access

Authors

Daniel De Backer · Erasmus Hospital

Patrick Biston · Grand Charleroi Hospital

Jacques Devriendt · Université Libre de Bruxelles

Christian Madl · Medical University of Vienna

Didier Chochrad · Centre hospitalier Etterbeek-Ixelles

César Aldecoa · Hospital Universitario Río Hortega

Alexandre Brasseur

Abstract

Although there was no significant difference in the rate of death between patients with shock who were treated with dopamine as the first-line vasopressor agent and those who were treated with norepinephrine, the use of dopamine was associated with a greater number of adverse events. (ClinicalTrials.gov number, NCT00314704.)

Topics & Keywords

Cardiac Arrest and Resuscitation Sepsis Diagnosis and Treatment Mechanical Circulatory Support Devices

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 362, Issue 9, pp. 779-789

DOI: 10.1056/nejmoa0907118

Field-Weighted Citation Impact: 88.51