Radiotherapy plus Concomitant and Adjuvant Temozolomide for Glioblastoma

200521,289 citationsJournal Articlebronze Open Access

Authors

Roger Stupp · University Hospital of Lausanne

Warren Mason · Princess Margaret Hospital

Martin J. van den Bent · Erasmus MC

Michael Weller · University of Tübingen

Barbara Fisher · Western University

Martin Taphoorn · University Medical Center Utrecht

Karl Bélanger ·

Abstract

The addition of temozolomide to radiotherapy for newly diagnosed glioblastoma resulted in a clinically meaningful and statistically significant survival benefit with minimal additional toxicity.

Topics & Keywords

Glioma Diagnosis and Treatment Brain Metastases and Treatment Medical Imaging Techniques and Applications

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 352, Issue 10, pp. 987-996

DOI: 10.1056/nejmoa043330

Field-Weighted Citation Impact: 172.75