Mortality after Fluid Bolus in African Children with Severe Infection

20111,575 citationsJournal Articlebronze Open Access

Authors

Kathryn Maitland · Wellcome Trust

Sarah Kiguli · Makerere University

Robert O. Opoka · Makerere University

Charles Engoru · Soroti Hospital

Peter Olupot‐Olupot · Mbale Hospital

Samuel Akech · Kenya Medical Research Institute

Richard Nyeko ·

Abstract

Fluid boluses significantly increased 48-hour mortality in critically ill children with impaired perfusion in these resource-limited settings in Africa. (Funded by the Medical Research Council, United Kingdom; FEAST Current Controlled Trials number, ISRCTN69856593.).

Topics & Keywords

Sepsis Diagnosis and Treatment Cardiac Arrest and Resuscitation Neonatal Respiratory Health Research

UN Sustainable Development Goals

Zero hunger

Publication Details

Published in: New England Journal of Medicine

Volume 364, Issue 26, pp. 2483-2495

DOI: 10.1056/nejmoa1101549

Field-Weighted Citation Impact: 66.53