Time Course of Tumor Metabolic Activity During Chemoradiotherapy of Esophageal Squamous Cell Carcinoma and Response to Treatment

2004460 citationsJournal Articlebronze Open Access

Authors

Hinrich Wieder · Klinikum rechts der Isar

Björn L.D.M. Brücher · Klinikum rechts der Isar

Frank Zimmermann · Klinikum rechts der Isar

Karen Becker · Klinikum rechts der Isar

Florian Lordick · Klinikum rechts der Isar

Ambros J. Beer · Klinikum rechts der Isar

Markus Schwaiger

Abstract

Changes in tumor metabolic activity after 14 days of preoperative chemoradiotherapy are significantly correlated with tumor response and patient survival. This suggests that FDG-PET might be used to identify nonresponders early during neoadjuvant chemoradiotherapy, allowing for early modifications of the treatment protocol.

Topics & Keywords

Esophageal Cancer Research and Treatment Pancreatic and Hepatic Oncology Research Medical Imaging Techniques and Applications

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of Clinical Oncology

Volume 22, Issue 5, pp. 900-908

DOI: 10.1200/jco.2004.07.122

Field-Weighted Citation Impact: 35.85