Advances in the Diagnosis of Human Opisthorchiasis: Development of Opisthorchis viverrini Antigen Detection in Urine

201594 citationsJournal Articlegold Open Access

Authors

Chanika Worasith · Khon Kaen University

Christine Kamamia · George Washington University

Anna Yakovleva · George Washington University

Kunyarat Duenngai · Phetchabun Rajabhat University

Chompunoot Wangboon · Khon Kaen University

Paiboon Sithithaworn · Khon Kaen University

Nattaya Watwiengkam

Abstract

The detection of OV-infection by the urine OV-ES assay showed much greater diagnostic sensitivity and diagnostic specificity than the current "gold standard" FECT method for the detection and quantification of OV infection. Due to its ease-of-use, and noninvasive sample collection (urine), the urine OV-ES assay offers the potential to revolutionize the diagnosis of liver fluke infection and provide an effective tool for control and elimination of these tumorigenic parasites.

Topics & Keywords

Parasites and Host Interactions Parasite Biology and Host Interactions Global Maternal and Child Health

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: PLoS neglected tropical diseases

Volume 9, Issue 10, pp. e0004157-e0004157

DOI: 10.1371/journal.pntd.0004157

Field-Weighted Citation Impact: 3.85