Gliadin, zonulin and gut permeability: Effects on celiac and non-celiac intestinal mucosa and intestinal cell lines

2005498 citationsJournal Articlegreen Open Access

Authors

Sandro Drago

Ramzi El Asmar · University of Maryland, Baltimore

Mariarosaria Di Pierro · University of Maryland, Baltimore

Maria Grazia Clemente · University of Maryland, Baltimore

A. Sapone · University of Maryland, Baltimore

Manjusha Thakar · University of Maryland, Baltimore

Giuseppe Iacono · University of Palermo

Abstract

Based on our results, we concluded that gliadin activates zonulin signaling irrespective of the genetic expression of autoimmunity, leading to increased intestinal permeability to macromolecules.

Topics & Keywords

Celiac Disease Research and Management Helicobacter pylori-related gastroenterology studies Digestive system and related health

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Scandinavian Journal of Gastroenterology

Volume 41, Issue 4, pp. 408-419

DOI: 10.1080/00365520500235334

Field-Weighted Citation Impact: 7.08