Prediction of RNA Polymerase II recruitment, elongation and stalling from histone modification data

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Authors

Yun Chen · University of Copenhagen

Mette Jørgensen · University of Copenhagen

Raivo Kolde · University of Tartu

Xiaobei Zhao · University of Copenhagen

Brian J. Parker · University of Copenhagen

Eivind Valen · University of Copenhagen

Jiayu Wen ·

Abstract

In this study we introduce a general framework to accurately predict the level of RNAPII recruitment, elongation, stalling and mRNA expression from chromatin signals. The versatility of the method also makes it ideally suited to investigate other genomic data.

Topics & Keywords

RNA modifications and cancer Genomics and Chromatin Dynamics Cancer-related molecular mechanisms research

Publication Details

Published in: BMC Genomics

Volume 12, Issue 1, pp. 544-544

DOI: 10.1186/1471-2164-12-544

Field-Weighted Citation Impact: 2.26

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Prediction of RNA Polymerase II recruitment, elongation and stalling from histone modification data

Authors

Abstract

Topics & Keywords

Publication Details