Reproducibility of Interferon Gamma (IFN-γ) Release Assays. A Systematic Review

201497 citationsReviewgreen Open Access

Authors

Saloua Tagmouti · Institute of Seismology

Madeline Slater · Stanford University

Andrea Benedetti · Montreal Heart Institute

Sandra V. Kik · McGill University Health Centre

Niaz Banaei · Stanford University

Adithya Cattamanchi · San Francisco General Hospital

John Metcalfe ·

Abstract

This systematic review shows substantial variability with repeat IFN-γ release assays testing even under identical conditions, suggesting that reversions and conversions around the existing cut-point should be interpreted with caution.

Topics & Keywords

Tuberculosis Research and Epidemiology Respiratory viral infections research Antimicrobial Resistance in Staphylococcus

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Annals of the American Thoracic Society

Volume 11, Issue 8, pp. 1267-1276

DOI: 10.1513/annalsats.201405-188oc

Field-Weighted Citation Impact: 6.65