Preanalytic Influence of Sample Handling on SELDI-TOF Serum Protein Profiles

2007148 citationsJournal Article

Authors

John F. Timms · Ludwig Cancer Research

Elif Arslan‐Low · University College London

Aleksandra Gentry‐Maharaj · University College London

Zhiyuan Luo · Royal Holloway University of London

Davy T’Jampens

Vladimir N. Podust

Jeremy Ford · University College London

Eric T. Fung

Abstract

Changes in preanalytical handling variables affect profiles of serum proteins, including proposed disease biomarkers. Proteomic analysis of samples from serum banks collected using less stringent protocols is applicable if all samples are handled identically.

Topics & Keywords

Advanced Proteomics Techniques and Applications Clinical Laboratory Practices and Quality Control Metabolomics and Mass Spectrometry Studies

Publication Details

Published in: Clinical Chemistry

Volume 53, Issue 4, pp. 645-656

DOI: 10.1373/clinchem.2006.080101

Field-Weighted Citation Impact: 11.60

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Preanalytic Influence of Sample Handling on SELDI-TOF Serum Protein Profiles

Authors

Abstract

Topics & Keywords

Publication Details