Western diet induces dysbiosis with increased <i>E coli</i> in CEABAC10 mice <i>,</i> alters host barrier function favouring AIEC colonisation

Western diet induces changes in gut microbiota composition, alters host homeostasis and promotes AIEC gut colonisation in genetically susceptible mice. These results support the multifactorial aetiology of CD and highlight the importance of diet in CD pathogenesis.