Stereochemical elucidation of the 1,4 polyketide amphidinoketide I

200313 citationsJournal Article

Authors

Louise Walsh · Unilever (United Kingdom)

Jonathan M. Goodman · Unilever (United Kingdom)

Abstract

The relative and absolute stereochemistry of amphidinoketide I has been determined by the total synthesis of all the diastereoisomers. Molecular modelling suggests that the natural product is not the thermodynamically preferred diastereoisomer.

Topics & Keywords

Synthetic Organic Chemistry Methods Microbial Natural Products and Biosynthesis Asymmetric Synthesis and Catalysis

UN Sustainable Development Goals

Zero hungerResponsible consumption and production

Publication Details

Published in: Chemical Communications

DOI: 10.1039/b309104j

Field-Weighted Citation Impact: 0.71