Breast Cancer Risk Following Bilateral Oophorectomy in <i>BRCA1</i> and <i>BRCA2</i> Mutation Carriers: An International Case-Control Study

Oophorectomy is an effective means of reducing the risk of breast cancer in carriers of BRCA1 mutations. The data suggest oophorectomy is protective in BRCA2 carriers as well, but needs to be confirmed in other studies.