Allele-specific binding of ZFP57 in the epigenetic regulation of imprinted and non-imprinted monoallelic expression

2015165 citationsJournal Articlehybrid Open Access

Authors

Ruslan Strogantsev · University of Cambridge

Felix Krueger · Babraham Institute

Kazuki Yamazawa · University of Cambridge

Hui Shi · University of Cambridge

Poppy A. Gould · University of Cambridge

Megan Goldman-Roberts · University of Cambridge

Kirsten R. McEwen ·

Abstract

The work described here uncovers further roles for ZFP57-mediated regulation of genomic imprinting and identifies a novel mechanism for genetically determined monoallelic gene expression.

Topics & Keywords

Genetic Syndromes and Imprinting Epigenetics and DNA Methylation Genetics and Neurodevelopmental Disorders

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Genome Biology

Volume 16, Issue 1, pp. 112-112

DOI: 10.1186/s13059-015-0672-7

Field-Weighted Citation Impact: 12.61