Total Synthesis of Epicoccin G

201185 citationsJournal Article

Authors

K. C. Nicolaou · Scripps Research Institute

Sotirios Totokotsopoulos · Scripps Research Institute

Denis Giguère · Scripps Research Institute

Ya-Ping Sun · University of California, San Diego

David Šarlah · Scripps Research Institute

Abstract

An expedient enantioselective total synthesis of epicoccin G and related dithiodiketopiperazines through a strategy featuring direct two-directional sulfenylation, photooxygenation, and Kornblum-DeLaMare rearrangement is described.

Topics & Keywords

Sesquiterpenes and Asteraceae Studies Synthesis of Indole Derivatives Marine Sponges and Natural Products

Publication Details

Published in: Journal of the American Chemical Society

Volume 133, Issue 21, pp. 8150-8153

DOI: 10.1021/ja2032635

Field-Weighted Citation Impact: 4.06

Command Palette

Total Synthesis of Epicoccin G

Authors

Abstract

Topics & Keywords

Publication Details