Transendocardial, Autologous Bone Marrow Cell Transplantation for Severe, Chronic Ischemic Heart Failure

20031,291 citationsJournal Article

Authors

Emerson C. Perin · Universidade Federal do Rio de Janeiro

Hans Fernando Rocha Dohmann · Universidade Federal do Rio de Janeiro

Radovan Borojević · Universidade Federal do Rio de Janeiro

Suzana A. Silva · Hospital Pró-Cardíaco

A Sousa · Universidade Federal do Rio de Janeiro

Cláudio Tinoco Mesquita · Hospital Pró-Cardíaco

Maria Isabel D. Rossi

Abstract

Thus, the present study demonstrates the relative safety of intramyocardial injections of bone marrow-derived stem cells in humans with severe heart failure and the potential for improving myocardial blood flow with associated enhancement of regional and global left ventricular function.

Topics & Keywords

Mesenchymal stem cell research Mechanical Circulatory Support Devices Transplantation: Methods and Outcomes

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Circulation

Volume 107, Issue 18, pp. 2294-2302

DOI: 10.1161/01.cir.0000070596.30552.8b

Field-Weighted Citation Impact: 72.57