Silver-Mediated Trifluoromethoxylation of Aryl Stannanes and Arylboronic Acids

2011211 citationsJournal Article

Authors

Chenghong Huang · Harvard University

Theresa Liang · Harvard University

Shinji Harada · Harvard University

Eunsung Lee · Harvard University

Tobias Ritter · Harvard University

Abstract

A silver-mediated cross-coupling of trifluoromethoxide with aryl stannanes and arylboronic acids to give aryl trifluoromethyl ethers is reported. This is the first report of a transition-metal-mediated C(aryl)-OCF(3) bond formation.

Topics & Keywords

Fluorine in Organic Chemistry Inorganic Fluorides and Related Compounds Catalytic C–H Functionalization Methods

UN Sustainable Development Goals

Clean water and sanitation

Publication Details

Published in: Journal of the American Chemical Society

Volume 133, Issue 34, pp. 13308-13310

DOI: 10.1021/ja204861a

Field-Weighted Citation Impact: 5.10