Toll‐Like Receptor 2<i>(TLR2)</i>Polymorphisms Are Associated with Reversal Reaction in Leprosy

2008144 citationsJournal Articlebronze Open Access

Authors

Pierre–Yves Bochud · Cancer Research Center

Thomas R. Hawn · Cape Town HVTN Immunology Laboratory / Hutchinson Centre Research Institute of South Africa

Ruby Siddiqui · University Hospital, Newark

Paul Saunderson · All Africa Leprosy Tuberculosis and Rehabilitation Training Centre

Sven Britton · Armauer Hansen Research Institute

Isaac Abraham · Armauer Hansen Research Institute

Abstract

These data suggest a significant role for TLR-2 in the occurrence of leprosy reversal reaction and provide new insights into the immunogenetics of the disease.

Topics & Keywords

Leprosy Research and Treatment Mycobacterium research and diagnosis Immune Response and Inflammation

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: The Journal of Infectious Diseases

Volume 197, Issue 2, pp. 253-261

DOI: 10.1086/524688

Field-Weighted Citation Impact: 8.75