Circulating Tumor Cell Number and Prognosis in Progressive Castration-Resistant Prostate Cancer

2007671 citationsJournal Article

Authors

Daniel C. Danila · Spanish Oncology Genitourinary Group

Glenn Heller · Cancer Research And Biostatistics

Gretchen A. Gignac · Spanish Oncology Genitourinary Group

Rita Gonzalez-Espinoza

Aseem Anand

Erika Tanaka · Spanish Oncology Genitourinary Group

Hans Lilja

Lawrence B. Schwartz · Memorial Sloan Kettering Cancer Center

Abstract

Baseline CTC was predictive of survival, with no threshold effect. The shedding of cells into the circulation represents an intrinsic property of the tumor, distinct from extent of disease, and provides unique information relative to prognosis.

Topics & Keywords

Prostate Cancer Treatment and Research Cancer Cells and Metastasis Cancer Genomics and Diagnostics

UN Sustainable Development Goals

Reduced inequalities

Publication Details

Published in: Clinical Cancer Research

Volume 13, Issue 23, pp. 7053-7058

DOI: 10.1158/1078-0432.ccr-07-1506

Field-Weighted Citation Impact: 18.52