Two novel genetic variants in the mineralocorticoid receptor gene associated with spontaneous preterm birth

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Authors

Inge Christiaens · Newcastle University

Q. W. Ang · University of Western Australia

Lindsay Gordon · Dartmouth College

Xin Fang · University of Alberta

Scott M. Williams · Vanderbilt University

Craig E. Pennell · University of Western Australia

David M. Olson ·

Abstract

This report demonstrates an association between mineralocorticoid receptor gene polymorphisms, rs17484063 and rs2883929, and preterm birth, supporting a role for genetics in the association between chronic maternal stress and preterm birth. Potentially, this information may be used to predicting the risk of having a preterm delivery.

Topics & Keywords

Preterm Birth and Chorioamnionitis Birth, Development, and Health Maternal Mental Health During Pregnancy and Postpartum

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: BMC Medical Genetics

Volume 16, Issue 1, pp. 59-59

DOI: 10.1186/s12881-015-0205-y

Field-Weighted Citation Impact: 0.87