Intra-arterial Prourokinase for Acute Ischemic Stroke

19993,071 citationsJournal Article

Authors

Anthony J. Furlan · Cleveland Clinic

Randall T. Higashida · University of California, San Francisco

Lawrence R. Wechsler · University of Pittsburgh

Michael Gent · McMaster University

Howard A. Rowley · University of California, San Francisco

Carlos S. Kase

Michael S. Pessin · Tufts University

Abstract

Despite an increased frequency of early symptomatic intracranial hemorrhage, treatment with IA r-proUK within 6 hours of the onset of acute ischemic stroke caused by MCA occlusion significantly improved clinical outcome at 90 days.

Topics & Keywords

Acute Ischemic Stroke Management Protease and Inhibitor Mechanisms Cerebrovascular and Carotid Artery Diseases

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: JAMA

Volume 282, Issue 21, pp. 2003-2003

DOI: 10.1001/jama.282.21.2003

Field-Weighted Citation Impact: 79.40