Multitarget Stool DNA Testing for Colorectal-Cancer Screening

20141,851 citationsJournal Article

Authors

Thomas F. Imperiale · Center for Innovation

David F. Ransohoff · University of North Carolina at Chapel Hill

Steven H. Itzkowitz · Icahn School of Medicine at Mount Sinai

Theodore R. Levin · Kaiser Permanente Walnut Creek Medical Center

Philip T. Lavin

Graham P. Lidgard · Exact Sciences (United States)

David A. Ahlquist · Mayo Clinic in Arizona

Abstract

In asymptomatic persons at average risk for colorectal cancer, multitarget stool DNA testing detected significantly more cancers than did FIT but had more false positive results. (Funded by Exact Sciences; ClinicalTrials.gov number, NCT01397747.).

Topics & Keywords

Colorectal Cancer Screening and Detection Genetic factors in colorectal cancer Gastric Cancer Management and Outcomes

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 370, Issue 14, pp. 1287-1297

DOI: 10.1056/nejmoa1311194

Field-Weighted Citation Impact: 73.33