Presence of B Cells in Tertiary Lymphoid Structures Is Associated with a Protective Immunity in Patients with Lung Cancer

2014788 citationsJournal Article

Authors

Claire Germain · Délégation Paris 5

Sacha Gnjatic · Memorial Sloan Kettering Cancer Center

Fella Tamzalit · Délégation Paris 5

Samantha Knockaert · Délégation Paris 5

Romain Remark · Délégation Paris 5

Jérémy Goc · Délégation Paris 5

Alice Lepelley ·

Abstract

B-cell density represents a new prognostic biomarker for NSCLC patient survival, and makes the link between TLS and a protective B cell-mediated immunity.

Topics & Keywords

Immunotherapy and Immune Responses Cancer Immunotherapy and Biomarkers Immune Cell Function and Interaction

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: American Journal of Respiratory and Critical Care Medicine

Volume 189, Issue 7, pp. 832-844

DOI: 10.1164/rccm.201309-1611oc

Field-Weighted Citation Impact: 12.65