Guidelines for the Evaluation of Immune Therapy Activity in Solid Tumors: Immune-Related Response Criteria

20093,206 citationsJournal Article

Authors

Jedd D. Wolchok · Memorial Sloan Kettering Cancer Center

Axel Hoos · Memorial Sloan Kettering Cancer Center

Steven O’Day · Memorial Sloan Kettering Cancer Center

Jeffrey S. Weber · Bristol-Myers Squibb (United States)

Omid Hamid · Memorial Sloan Kettering Cancer Center

Célèste Lebbé · Bristol-Myers Squibb (United States)

Michele Maio

Abstract

Systematic criteria, designated immune-related response criteria, were defined in an attempt to capture additional response patterns observed with immune therapy in advanced melanoma beyond those described by Response Evaluation Criteria in Solid Tumors or WHO criteria. Further prospective evaluations of the immune-related response criteria, particularly their association with overall survival, are warranted.

Topics & Keywords

Immunotherapy and Immune Responses Cancer Immunotherapy and Biomarkers CAR-T cell therapy research

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Clinical Cancer Research

Volume 15, Issue 23, pp. 7412-7420

DOI: 10.1158/1078-0432.ccr-09-1624

Field-Weighted Citation Impact: 27.75

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