Detection of Aberrant Methylation of Four Genes in Plasma DNA for the Detection of Breast Cancer

2006243 citationsJournal Articlebronze Open Access

Authors

Mohammad Obaidul Hoque · Cheikh Anta Diop University

Qinghua Feng · Johns Hopkins University

Papa Souleymane Touré · Cheikh Anta Diop University

Amadou Dem · Cheikh Anta Diop University

Cathy W. Critchlow · Cheikh Anta Diop University

Stephen E. Hawes · Johns Hopkins University

Troy Wood

Abstract

These data suggest that epigenetic markers in plasma may be of interest for detection of breast cancer. Identification of additional breast cancer specific methylated genes with higher prevalence in early stage cancers would improve this approach.

Topics & Keywords

Epigenetics and DNA Methylation Cancer-related gene regulation Cancer Genomics and Diagnostics

Publication Details

Published in: Journal of Clinical Oncology

Volume 24, Issue 26, pp. 4262-4269

DOI: 10.1200/jco.2005.01.3516

Field-Weighted Citation Impact: 6.76

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Detection of Aberrant Methylation of Four Genes in Plasma DNA for the Detection of Breast Cancer

Authors

Abstract

Topics & Keywords

Publication Details