Gene-Wide Analysis Detects Two New Susceptibility Genes for Alzheimer's Disease

20141,405 citationsJournal Articlegold Open Access

Authors

Valentina Escott‐Price · Cardiff University

Céline Bellenguez · Institut Pasteur de Lille

Li‐San Wang · University of Pennsylvania

Seung‐Hoan Choi · Boston University

Denise Harold · Cardiff University

Lesley Jones · Cardiff University

Peter Holmans ·

Abstract

The additional genes identified in this study, have an array of functions previously implicated in Alzheimer's disease, including aspects of energy metabolism, protein degradation and the immune system and add further weight to these pathways as potential therapeutic targets in Alzheimer's disease.

Topics & Keywords

Alzheimer's disease research and treatments Bioinformatics and Genomic Networks Genetic Associations and Epidemiology

Publication Details

Published in: PLoS ONE

Volume 9, Issue 6, pp. e94661-e94661

DOI: 10.1371/journal.pone.0094661

Field-Weighted Citation Impact: 103.50

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Gene-Wide Analysis Detects Two New Susceptibility Genes for Alzheimer's Disease

Authors

Abstract

Topics & Keywords

Publication Details